597 private links
More videos at the original post, but I would like to highlight these videos:
- How do vaccines work? Kelwalin Dhanasarnsombut, Ted-Ed (2015) Good general introduction.
- How fast can a vaccine be made? Dan Kwartler, Ted-Ed (Jun 2020)
- mRNA vaccines A slightly technical but nonetheless approachable explainer of how mRNA vaccines work (the basis of both Pfizer-BioNTech's and Moderna's COVID-19 vaccine).
And not to forget, Wikipedia has an excellent article on the current state of our COVID-19 vaccines.
We estimate COVID risk in units of microCOVIDs, where 1 microCOVID = a one-in-a-million chance of getting COVID.
Compare with the concept of micromort.
Via FlowingData
Dr. Iman Abuzeid is the co-founder and CEO of Incredible Health, a digital platform that helps streamline the hiring process for nurses and recruiting hospitals. After seeing an increased demand for nurses in April, and a shift to hiring digitally, the platform has now been able to expedite the hiring process to 15 days or less, compared to an industry standard of 90 days.
From City University of New York, a paper on a bit of the physics relevant to the pandemic - specifically the issue of aerosolized droplets and air circulation in rooms.
The conclusion is that, based on common convection patterns, the 2 meter separation rule is not enough in the absence of a properly designed air filtration system.
Via nanoscale views
In light of current events, here's an excellent primer on the chemistry of soap.
Also available via my wallabag
Excellent piece by Ed Yong in the Atlantic.
Via kottke.org which has a nice write-up of the video.
Good explanation of exponential growth and how it relates to health-care capacity in light of the current SARS-CoV-2 virus outbreak.
Of course, virus transmission is in fact logistic, not exponential, but this video by Sharafestien nonetheless does a good job of driving home the main point: why it is prudent for everyone to take precautions.
From Patrick Collison's review:
World Bank data indicate that 3.7 billion people, about half the world’s population, are exposed to more than 50 µg/m³ of PM2.5 on an annual basis, 5x the unit of measure for most of the findings below.
- Substantial declines in short-term cognitive performance after short-term exposure to moderate (median 27.0 µg/m³) PM2.5 pollution: “The results from the MMSE test showed a statistically robust decline in cognitive function after exposure to both the candle burning and outdoor commuting compared to ambient indoor conditions. The similarity in the results between the two experiments suggests that PM exposure is the cause of the short-term cognitive decline observed in both.” […] “The mean average [test scores] for pre and post exposure to the candle burning were 48 ± 16 and 40 ± 17, respectively.” – Shehab & Pope 2019.
- Chess players make more mistakes on polluted days: “We find that an increase of 10 µg/m³ raises the probability of making an error by 1.5 percentage points, and increases the magnitude of the errors by 9.4%. The impact of pollution is exacerbated by time pressure. When players approach the time control of games, an increase of 10 µg/m³, corresponding to about one standard deviation, increases the probability of making a meaningful error by 3.2 percentage points, and errors being 17.3% larger.” – Künn et al 2019.
- A 3.26x (albeit with very wide CI) increase in Alzheimer’s incidence for each 10 µg/m³ increase in long-term PM2.5 exposure? “Short- and long-term PM2.5 exposure was associated with increased risks of stroke (short-term odds ratio 1.01 [per µg/m³ increase in PM2.5 concentrations], 95% CI 1.01-1.02; long-term 1.14, 95% CI 1.08-1.21) and mortality (short-term 1.02, 95% CI 1.01-1.04; long-term 1.15, 95% CI 1.07-1.24) of stroke. Long-term PM2.5 exposure was associated with increased risks of dementia (1.16, 95% CI 1.07-1.26), Alzheimer’s disease (3.26, 95% 0.84-12.74), ASD (1.68, 95% CI 1.20-2.34), and Parkinson’s disease (1.34, 95% CI 1.04-1.73).” – Fu et al 2019. Similar effects are seen in Bishop et al 2018: “We find that a 1 µg/m³ increase in decadal PM2.5 increases the probability of a dementia diagnosis by 1.68 percentage points.”
- A study of 20,000 elderly women concluded that “the effect of a 10 µg/m³ increment in long-term [PM2.5 and PM10] exposure is cognitively equivalent to aging by approximately 2 years”. – Weuve et al 2013.
- “Utilizing variations in transitory and cumulative air pollution exposures for the same individuals over time in China, we provide evidence that polluted air may impede cognitive ability as people become older, especially for less educated men. Cutting annual mean concentration of particulate matter smaller than 10 µm (PM10) in China to the Environmental Protection Agency’s standard (50 µg/m³) would move people from the median to the 63rd percentile (verbal test scores) and the 58th percentile (math test scores), respectively.” – Zhang et al 2018.
- “Exposure to CO2 and VOCs at levels found in conventional office buildings was associated with lower cognitive scores than those associated with levels of these compounds found in a Green building.” – Allen et al 2016. The effect seems to kick in at around 1,000 ppm of CO2.